Furthermore, we included the covariables of age, gender, race, and tumor purity for a Cox proportional hazard model and observed the association between the poor prognosis of LGG and high expression of GAS2L2 (Table S1, Cox_p < 0.001, HR = 1.315), GAS2L3 (Cox_p < 0.001, HR = 1.526), and low‐expression GAS2L1 (Cox_p = 0.010, HR = 0.642). This evidence concerns the gene GAS2L1 and neoplasm.