CAMK2G and Cerebral ischemia: Xiao-Juan et al. reported similar observations that cerebral ischemia led to reduced p-CaMKII (T286) in the hippocampal CA1 pyramidal neurons, which associates with decreased spatial learning and memory capacity of mice subjected to right unilateral common carotid artery occlusion (a chronic VaD model) at 30 days after surgery [134].