The same group reported in another study using a bilateral common carotid artery stenosis mouse model (BCCAS, a common model of cerebral hypoperfusion–induced cognitive impairment) that CaM inhibitor DY-9836 restored the decrease of p-CaMKII (T286) in hippocampal pyramidal neurons and improved learning impairment after BCCAS surgical operation [135]. The gene discussed is CAMK2G; the disease is Cognitive impairment.