Significant reduction in lymphocyte count, and marked increase in C-reactive protein (CRP), alanine amino-transferase (ALT), aspartate aminotransferase (AST), direct bilirubin (DBIL), and glucose were exhibited in severe COVID-19 patients, which were consistent with previous findings1,30 (Supplementary Fig. 1 and Supplementary Data 1). This evidence concerns the gene GPT and COVID-19.