Immunofluorescence stainings for CD3 and S100B verified the presence of CD3+ T-cells within the S100B+ SC stroma in GNs (Supplementary Fig. 6a), while CD3+ T-cells were only sparsely detected in the tumor cell portion of NBs (Supplementary Fig. 6b,c). Here, S100B is linked to Nijmegen breakage syndrome.