SYNGR1 and systemic lupus erythematosus: Consistent with our results at the C4A and SYNGR1 loci, variant overlapping TFs include members of the ETS (e.g., ELF1) and ATF-like (e.g., ATF7) families, along with other TFs whose genetic loci are associated with SLE, including IRF544 (Fig. 5c and Supplementary Data 15).