In addition, modifying PRDX1 expression in CRC cells did not influence either the mRNA or protein expression of SAG (RNF7), a well-known adaptor for UBE2F and CUL549; moreover, SAG was also present in the anti-PRDX1 immunoprecipitate (Figs. S7 and S8). The gene discussed is SAG; the disease is colorectal carcinoma.