CASP3 and neoplasm: The effects of short-time treatment with WEHI-7326 on the 24 T tumor cells was further studied in vivo and compared to docetaxel (Supplementary Fig. S11): at 16 h post single-dose treatment, a reduction in proliferation (Ki67 expression) and increased induction of apoptosis (cleaved/activated caspase-3) was found in both treatment groups but was significantly higher in the WEHI-7326 arm.