ZEB1 and cancer: When overexpressed from lentiviral vectors in TSU and HOC313 cells, which express endogenous EHF-SF only at low levels (see Fig. 2D), the EHF-SF-L285P mutation no longer downregulated ETS1 and ZEB1, inhibited motility, and sensitized cells to anti-cancer drug (Fig. 6F, G, H).