Immunostaining of orthotopic tumor sections with an anti-NF-κB antibody showed similar levels of NF-κB-positive staining in irradiated IGFBP3-expressing tumor cells (n = 5; Immunoreactivity score (IRS): 8 per section) compared to controls (n = 5; IRS: 5.8 ± 1.02 per section; Fig. 6f, g). The gene discussed is IGFBP3; the disease is neoplasm.