CRP and rheumatoid arthritis: Notably, a newly introduced and novel parameter defined as the ratio of CRP to ALB (CAR), has been proposed as more valuable and accurate than either CRP or ALB alone in predicting inflammatory status and prognosis in various clinical settings, including the stable angina pectoris [32, 33], colorectal cancer [34, 35], coronary artery ectasia [36], inflammatory bowel disease [37], Takayasu arteritis [38], rheumatoid arthritis [39] and sepsis [40].