SOCS6 and esophageal squamous cell carcinoma: In transwell assays, the migration ability of ESCC cells stably overexpressing SOCS6 was decreased (Fig. 3e, f, P < 0.001), whereas cells with knockdown of SOCS6 did not alter cell motility (Fig. 3 g, h, Eca109: P = 0.43, KYSE-150: P = 0.20).