Adenocarcinomas (n = 12) had a significantly higher presence of CD18 positive cells when compared with adenomas (n = 18) [Kruskal-Wallis test, 1.75 (1–2) vs 1 (0–1.5), p = 0.05, Fig. 1c and d]. This evidence concerns the gene ITGB2 and adenocarcinoma.