In the EMTUs we analyzed the expression of the TGF-β1-induced FMT-related genes such as ACTA2 (encoding α-SMA, the main marker of myofibroblasts, TAGLN (encoding transgelin - a smooth muscle marker and unique actin-binding protein involved in asthma), FN1 (fibronectin – ECM protein important in subepithelial fibrosis in asthma) and TNC (tenascin C – ECM protein, biomarker for asthma). The gene discussed is TNC; the disease is fibrosis.