SLC5A3 and Dravet syndrome: Elevated levels of mIns have also been found in amniotic fluid of human DS pregnancies (15–18 weeks GA) (Santamaria et al., 2014) SMIT1 is overexpressed in human DS and associated with increased intracellular levels of mIns in adults (Shonk and Ross, 1995; Cárdenas et al., 2017).