After testing only genome-wide significant inflammation-related SNPs for cardiometabolic traits, we found evidence for associations of inflammation-related genetically-predicted fasting insulin (Wald Ratio OR = 2.95; 95% C.I., 1.38–6.34; corrected p = 0.035) and HDL (Wald Ratio OR = 0.55; 95% CI, 0.36–0.84; corrected p = 0.035) with schizophrenia. Here, INS is linked to schizophrenia.