Studies have also reported the roles of HIF1A-AS2 in tumors, such as HIF1A-AS2 targeting miR-548c-3p in breast cancer31, sponging miR-129-5p in colorectal cancer and miR-33b-5p in osteosarcoma37,41, sponging miR-665 in osteogenic differentiation38, and sponging miR-153-3p in human umbilical vein cells56. The gene discussed is HIF1A; the disease is colorectal cancer.