HIF1A and renal carcinoma: Cells that were continuously transfected with pcDNA3.1-HIF1A-AS2 and co-incubated with IWR-1 showed stronger inhibitory effects on cell proliferation (Figure 5H) and migration (Figure 5I) of kidney carcinoma cells, with comparison to the pcDNA3.1-HIF1-AS2+DMSO group.