For example, Zhang et al.35 found that by adsorbing miR-149-5p, upregulated circNRIP1 in GC increased the expression level of mammalian target of rapamycin (mTOR) to activate the AKT1/mTOR signaling pathway, thus accelerating energy anabolism and inhibiting autophagy-related catabolism of GC cells. This evidence concerns the gene AKT1 and gastric cancer.