Additionally, unlike vehicle‐treated castrated samples, IVM‐treated samples demonstrated reduced PSA levels (Fig 6E upper panel), tumor growth (Fig 6E lower panel), p‐CAMKK2/p‐p38/p‐Hsp27 axis activity, and AR levels compared with pre‐castration samples (Fig 6F). This evidence concerns the gene CAMKK2 and neoplasm.