Recently, alterations in the executive function of verbal fluency associated with a loss of structural integrity were observed in presymptomatic C9orf72 carriers [7], i.e., in subjects with a hexanucleotide GGGGCC-repeat expansion in C9orf72 which is the most prevalent genetic cause of ALS and frontotemporal dementia (FTD) in Caucasian populations [8]. The gene discussed is C9orf72; the disease is frontotemporal dementia.