In addition, intermediate autosomal osteopetrosis (IAO) and the milder, autosomal dominant osteopetrosis type 2 (ADO2, or Albers-Schönberg disease) are caused by CLCN7 mutations (Cleiren et al., 2001; Frattini et al., 2003; Sobacchi et al., 2013). This evidence concerns the gene CLCN7 and osteopetrosis.