Fusobacterium nucleatum, an oral anaerobic commensal, has been shown to home preferentially to malignant mammary tissue as compared to normal adjacent tissue through binding of bacterial Fap2 to tumor Gal-GalNAc sites, and induce a pro-tumorigenic inflammation by reducing CD 4+ and CD8+ T cell infiltration, thus leading to increased tumor growth and metastasis (33). Here, CD8A is linked to neoplasm.