CD4 and neoplasm: They observed that in the AVATAR mice generated by fecal microbiota transplantation (FMT) from PD-1 non-responders, oral supplementation with A. muciniphila restored the efficacy of PD-1 blockade in an interleukin-12-dependent manner and led to the recruitment of CCR9+CXCR3+CD4+ T lymphocytes into mouse tumor beds (12).