CD24 and Sepsis: Although the role of Siglec-G in B-1a cells in the context of sepsis has not been studied before, given the evidence of Siglec-G-mediated anti-inflammatory role in CD24 expressing myeloid cells (20), it is speculated that B-1a cells which also express CD24 and Siglec-G could play similar anti-inflammatory role in sepsis (21).