It has been demonstrated that there is a direct correlation between the levels of IL-1β, IL-6, IL-8, TNF-α, IL-10 and COVID-19 central inflammatory complications such as neuromyelitis optica (also known as Devic's disease), transverse myelitis, acute disseminated encephalomyelitis, amyotrophic lateral sclerosis, herpes simplex encephalitis, Parkinson’s disease, traumatic brain injury, epilepsy, and stroke (Vezzani et al., 2002; Rodney et al., 2018; Vezzani et al., 2019; West et al., 2019). This evidence concerns the gene TNF and COVID-19.