The aforementioned effects of theaflavins, as well as its antiviral potentials (Zu et al., 2012), could introduce it as a useful treatment against the neurological sign of COVID-19, via modulation of neuronal IL-1β, IL-6, TNF-α, IL-10, glial fibrillary acidic protein and Bax. The gene discussed is IL1B; the disease is COVID-19.