TP53 and cancer: The main enriched pathways in HepG2 cells were represented including pathways related to transcriptional misregulation in cancers, pathways in cancers, microRNAs in cancers, PI3K-Akt signaling pathway, TGF-β signaling pathway, Hippo signaling pathway, p53 signaling pathway, and Rap1 signaling pathway (Figure 7B).