NFE2L2 and Friedreich ataxia: Considering that the GSH-related genes are regulated by NRF2, whose expression is impaired in FRDA patients and in preclinical models of FXN deficiency (Paupe et al., 2009; D’Oria et al., 2013; Shan et al., 2013; La Rosa et al., 2019, 2020d; Petrillo et al., 2019; Turchi et al., 2020b), we evaluated if NRF2 might be differently expressed in the family.