We found two additional mutations in the sarcoma tissue for AKT2 (chromosome 19; position (GRCh37) 40742052) and NRAS (chromosome 1; position (GRCh37) 115256669) with a frequency of 26% and 48%, respectively; these two mutations were not present in the initial biopsy or in the resection specimen (Fig. 4) and present intronic mutations with no effect on the protein structure. This evidence concerns the gene AKT2 and sarcoma.