Future directions of study should include characterization of (i) the expression of OATP1B3 isoforms in mCRPC tissues, (ii) the function of CT-OATP1B3 in prostate cancer, and (iii) tumoral androgen uptake kinetics in those cancers with high gadoxetate disodium enhancement. The gene discussed is SLCO1B3; the disease is Familial prostate cancer.