Importantly, higher Ki67 reflecting increased number of mitotic cells was observed in the MCF7shMAGI1 tumors (Fig. 2B–D) and among the proliferative tumor cells, the Ki67 staining was more intense (Fig. 2E), showing that indeed MAGI1-deficient cells proliferate more, and suggesting that the increased tumor growth upon MAGI1 depletion is primarily due to increased tumor cells burden. Here, MKI67 is linked to neoplasm.