Even though BCa was the prime focus of this study, the effects of MAGI1 knockdown appeared not restricted to mammary cells, and similar observations on anchorage-free growth in soft agar, and orthotopic tumor growth in nude mice were also observed using HCT116 colon cancer cells (Supplementary Fig. S4E-G) extending earlier reports34. The gene discussed is MAGI1; the disease is malignant colon neoplasm.