Of the 35 patients, 3 (15.8% of the 19 with molecular diagnosis) had EGFR gene amplification while 27 (77.1%) presented positive EGFR protein expression, Fig. 5C. These tumors were also stratified by IDH and tumor protein 53 (TP53) mutations to determine the influence of these mutations on the molecular profile of a given tumor. This evidence concerns the gene TP53 and neoplasm.