With anti-CXCL11, similar results were observed in IHC staining, in which CXCL11 proteins were significantly increased in nonmetastatic HCC tissue samples and metastatic HCC tissue samples, and greater in the metastatic HCC tissues than the nonmetastatic HCC tissues (Fig. 1G). This evidence concerns the gene CXCL11 and hepatocellular carcinoma.