LOXHD1 and hearing loss disorder: Mutations in LOXHD1 cause DFNB77, a human nonsyndromic recessive form of hearing loss (Grillet et al., 2009b) that can manifest at birth or later in life and shows various degrees of progression, preferentially affecting the high and middle hearing frequencies (Grillet et al., 2009b; Edvardson et al., 2011; Eppsteiner et al., 2012; Vozzi et al., 2014; Atik et al., 2015; Mori et al., 2015; Minami et al., 2016; Wesdorp et al., 2018; Maekawa et al., 2019).