The survival analysis showed that the TXNRD2 gene was associated with poor prognoses of SKCM and UVM, but good prognoses of LGG, KIRP, PAAD, and PRAD, while the TXNRD3 gene was correlated with poor prognoses of KICH, PAAD, THCA, THYM, and UCEC. This evidence concerns the gene TXNRD3 and pancreatic adenocarcinoma.