In addition, miR 125a-5p could increase SIRT7 and also raised apoptosis in lung cancer cells to rise their radiosensitivity and miR-22 suppresses cancerogenesis and enhances radiosensitivity of breast cancer cells by selecting SIRT1, supplying a hopeful therapeutic objective for breast cancer [21,22]. The gene discussed is SIRT1; the disease is breast carcinoma.