A shortlist of eleven targets was selected for quantification by qPCR by p‐value, prior annotation in circBase, and biological interest of the parent gene to Alzheimer's Disease pathophysiology: MAP3K4: hsa_circ_0078619, TBCK: hsa_circ_0007540, FGD6: hsa_circ_0099549, IGF2R: hsa_circ_0131235, SOBP: hsa_circ_0001633, PGAP1: hsa_circ_0003394, RABGAP1: hsa_circ_0137854, FAM126A: hsa_circ_0008951, GAS2: hsa_circ_0095626, CLASP1: hsa_circ_0007052, and CDKL5: hsa_circ_0089980. The gene discussed is FGD6; the disease is early-onset autosomal dominant Alzheimer disease.