Meanwhile, the immune‐warm phenotype just followed the steps below the immune‐hot subtype and showed the relative association with both immunoactivity and immunosuppression, overlapping with ICOS, TNFSF13B, and CD48 as costimulators and CTLA‐4, TIGIT, and HAVCR2 as coinhibitors among the top‐three‐strong correlation between checkpoint expression and tumor‐infiltrating cells (Figure 4E). The gene discussed is HAVCR2; the disease is neoplasm.