Mutations in TARDBP, the gene encoding the TDP‐43 protein are a cause of familial ALS, and in rare cases also of ALS‐FTD or FTD (Kabashi et al, 2008; Sreedharan et al, 2008; Van Deerlin et al, 2008; Lemmens et al, 2009; Borroni et al, 2009; Caroppo et al, 2016). The gene discussed is TARDBP; the disease is amyotrophic lateral sclerosis.