Moreover, we observed that mutant TDP‐43 causes axonal transport defects as observed previously in models of SOD1 (Kiskinis et al, 2014), C9ORF72 (Fumagalli et al, 2019; Abo‐rady et al, 2020), and FUS (Guo et al, 2017), further implicating this mechanism in the pathogenesis of ALS/FTD. This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.