The anti-tumor activity of different tanshinone IIA preparations in HepG2 and Huh7 cells was as follows: Gal-pH-TanIIA-NSVs (1.481, 1.539 μg/mL) > Gal-TanIIA-NSVs (2.185, 2.252 μg/mL) ≈ Free TanIIA (2.256, 2.505 μg/mL) > pH-TanIIA-NSVs (3.042, 3.627 μg/mL) > TanIIA-NSVs (4.419, 5.108 μg/mL) (Fig. 4c). Here, GAL is linked to neoplasm.