KLRK1 and Miyoshi myopathy: Since the blockade of NKG2D and NKp30 does not lead to a complete or near complete abolition of the NKAE cell activity, this raises the need for further in-depth studies of other highly expressed molecules like the co-stimulatory molecule DNAM-1 which has been shown to be related with oxidative stress conditions that may occur in MM [44].