We incorporated 21 items with relatively high AUC into a multivariable model and found that cerebrovascular disease (CVD; HR, 6.162), prothrombin activity (PTA; HR, 0.912), blood urea nitrogen (BUN; HR, 1.207), and IL-6 (HR, 1.085) were independent predictors for fatality (Supplementary Table 6). This evidence concerns the gene F2 and cerebrovascular disorder.