SEPTIN9 and colorectal carcinoma: They found that a number of biomarkers of DNA hypermethylation including the known (e.g., SEPT9 and IKZF1) and the novel (e.g. TJP2, EMBP1, APBB1IP, CHST11, and KCNQ5) genes were detected in cfDNA of CRC (Li et al., 2019).