SGK3 and ischemic stroke: Additionally, GSVA showed oligodendrocyte subcluster 9 was enriched in IL-6, complement, TNF-α pathway, and Kras signaling, suggesting that Sgk3 from oligodendrocytes may play an important role regulating oligodendrocyte viability and inflammatory responses during the acute stage of ischemic stroke (Inoue et al., 2016).