The effect of five SNPs that showed to be the most statistically associated with the Kawasaki disease in this study was evaluated, this includes: rs12037447 in non-coding sequence and rs146732504 in KIF25, rs151078858 in PTPRJ, rs55723436 in SPECC1L, rs6094136 in RPN2 genes (Table 3). This evidence concerns the gene RPN2 and Kawasaki disease.