YTHDF2 inhibited adhesion, invasion, migration, and Epithelial-Mesenchymal Transition (EMT) through the YAP signal and promoted the proliferation of pancreatic cancer cells through the Serine/threonine-protein kinases/Glycogen synthase kinase 3 beta/Cyclin D1 (AKT/GSK3B/CCND1) pathway (35). This evidence concerns the gene GSK3B and familial pancreatic carcinoma.