YTHDF3 expression in BC brain metastases is higher than that in BC and nontumor tissues, and facilitates expressions of ST6 N-Acetylgalactosaminide Alpha-2,6-Sialyltransferase 5 (ST6GALNAC5), gap junction proteinα1 (GJA1), EGFR, and vascular endothelial growth factor A (VEGFA) in a m6A-dependent manner during the regulation of multiple steps in brain metastases (40). The gene discussed is YTHDF3; the disease is breast cancer.