In addition, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis about the regulation of esophageal squamous cell carcinoma (ESCC) by YTHDC2 revealed that YTHDC2 is associated with p53, NF-kappa B and JAK-STAT signaling pathways (31). Here, YTHDC2 is linked to esophageal squamous cell carcinoma.