As shown in the boxplot (Figures 5F-K), the expression of CXCR4, PLOD2, and HPR was significantly upregulated in patients with GC, while the expression of DYNLL1 and PGK2 was significantly downregulated in patients with GC in the GEO dataset (p < 0.05; Figures 5F-K). The gene discussed is PLOD2; the disease is gastric cancer.