Consistent with the role of NETs in bacterial infections, genes involved in the recognition and uptake of bacteria, including TLR- and NOD-like receptor signaling, and FcγR-mediated phagocytosis were enriched in Endotype A; notably FcγRIIA and the phagocytic pathway downstream of this receptor were significantly (p-value = 0.025) enriched in Endotype A. This evidence concerns the gene FCGR2A and bacterial infectious disease.