TNC and myocarditis: TN-C is rarely expressed in normal adult hearts but is upregulated under pathological conditions with tissue injury, tissue repair/regeneration, and inflammation (38, 39), including myocarditis (40, 41), DCM (42), rheumatic heart disease (43), myocardial infarction (44, 45), hypertensive heart disease (46), and Kawasaki disease (47).