Nonetheless, in a study published by our group in 2014 evaluating subpopulations of monocytes in patients with different degrees of fibrosis secondary to schistosomiasis, we observed higher intracellular levels of TGF-β in classic, intermediate, and non-classic monocytes in individuals with moderate to severe fibrosis compared to individuals without fibrosis or individuals with incipient fibrosis (12). The gene discussed is TGFB1; the disease is schistosomiasis.