NLRs have a variety of immune functions, including response to infection and the formation of inflammasomes (NLRP1, NLRP3, and NLRC4) (61, 62), regulation of antigen presentation (NLRC5, CIITA) (63, 64), regulation of homeostasis in microbial clusters (NLRP6), and a regulatory role in the responses of nuclear factor kappa B (NF-кB) (NLRP6, NLRP12, and NLRC3), MAVS (NLRX1), and STING (NLRC3, NLRX1) (65–68). Here, NLRX1 is linked to infection.