Moreover, Siglec-7 expression on CD56bright NK cells increased in patients with advanced fibrosis, which differed from the finding with CD56dim cells (Supplementary Figure 2 and Figure 3B), whereas Siglec-9, NKp30, NKp46, PD-1, and ILT2 were expressed at comparable levels on CD56bright NK cells from NAFLD patients and HVs (Supplementary Figure 2). The gene discussed is PDCD1; the disease is metabolic dysfunction-associated steatotic liver disease.