Compared to normal tissue samples, KIAA1429, HNRNPC, METTL3, WTAP, YTHDC1, and FTO were down-regulated in ACC, and RBM15, ZC3H13, YTHDF1, YTHDF2, and ALKBH5 were up-regulated in ACC (Figure 1B). The gene discussed is METTL3; the disease is adrenal cortex carcinoma.